Question: AJ is a 50-year-old white male who presents for follow-up of his hypertension. AJ is not a diabetic and has normal renal function. He is adherent with a low-sodium diet, exercises 150 minutes weekly, and is taking his hydrochlorothiazide 25mg po daily. His home blood pressure logs and the clinic reading reveal blood pressures in the range 150-160/90-100. The rest of his vitals including heart rate are normal, as is his examination. He has no known drug allergies. His only other medication is cetirizine 10mg po daily for allergic rhinitis.

  • What is the mechanism of action of hydrochlorothiazide, and is it an appropriate treatment for AJ?
  • What do you recommend to do to AJ’s regimen to reach his goals?
  • Do you have any counseling points and monitoring parameters for AJ’s plan of care?

Answer: Hydrochlorothiazide is available under various brands, such as Oretic, Microzide, Hydrochlorot and Esidrex…….